OUR SCIENCE
PARTNERING
Chronic & Metabolic Diseases
Restoring Cellular Adaptation in Chronic Diseases
A Shared Mechanism Across
Chronic Diseases
Chronic diseases are driven by persistent metabolic stress that disrupts how cells function and respond to their environment
Lung diseases
Epithelial injury • Macrophage lipid loading • Chronic inflammation • Fibrotic remodeling
Cardiovascular diseases
Platelet activation • Endothelial dysfunction • Foam cell formation • Pro-thrombotic signaling
Chronic kidney diseases
Tubular ferroptosis • Macrophage-driven inflammation • Fibrotic remodeling • Progressive tissue injury
Metabolic diseases
Lipid overload • Adipose inflammation • Insulin resistance • Systemic metabolic dysfunction
Lung Diseases
Epithelial injury • Macrophage lipid loading • Chronic inflammation • Fibrotic remodeling
Cardiovascular Diseases
Platelet activation • Endothelial dysfunction • Foam cell formation • Pro-thrombotic signaling
Chronic kidney diseases
Tubular ferroptosis • Macrophage-driven inflammation • Fibrotic remodeling • Progressive tissue injury
Metabolic diseases
Lipid overload • Adipose inflammation • Insulin resistance • Systemic metabolic dysfunction
We target metabolic checkpoints to correct maladaptive stress responses, resolving chronic inflammation and restoring tissue function
Therapeutic outcome through
Metabolic Reprogramming
Immune Cells
Orchestrate and resolve inflammation
Endothelial Cells
Regulate vascular tone, permeability and repair
Epithelial Cells
Maintain barrier integrity and tissue homeostasis
